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Master of Science Biochemistry and Specialization in Human and Molecular Genetics

The Master of Science in Biochemistry with a specialization in Human and Molecular Genetics is a research-based program that prepares candidates for a variety of careers in teaching and research both within and outside of academia.

Program Description

Graduate students are actively involved in laboratory research, course work, and presentation of research seminars. Thus, they acquire autonomy in conducting research and in preparing publications. The programs create a stimulating and challenging environment which will allow students to achieve excellence in research. Graduates of the programs must demonstrate research skills and credibility as professionals in their area of research.

Collaborative Program Description

The Faculty of Medicine offers a collaborative program in Human and Molecular Genetics at the master's and doctoral levels. The primary graduate programs in Biochemistry (BCH), Cellular and Molecular Medicine (CMM) and Neuroscience (NSC) collaborate in offering the specialization. The degree awarded specifies the primary program and indicates "specialization in Human and Molecular Genetics."

Main Areas of Research

• General biochemistry
• Molecular biology
• Nutrition and metabolism

Other Programs Offered Within the Same Discipline or in a Related Area

• Master of Science Biochemistry (MSc)
• Master of Science Biochemistry Specialization in Bioinformatics (MSc)
• Master of Science Biochemistry Specialization in Pathology and Experimental Medicine (MSc)
• Doctorate in Philosophy Biochemistry (PhD)
• Doctorate in Philosophy Biochemistry Specialization in Human and Molecular Genetics (PhD)
• Doctorate in Philosophy Biochemistry Specialization in Pathology and Experimental Medicine (PhD)
• Master of Science Cellular and Molecular Medicine Specialization in Human and Molecular Genetics (MSc)
• Master of Science Neuroscience Specialization in Human and Molecular Genetics (MSc)
• Doctorate in Philosophy Cellular and Molecular Medicine Specialization in Human and Molecular Genetics (PhD)
• Doctorate in Philosophy Neuroscience Specialization in Human and Molecular Genetics (PhD)

Fees and Funding

The estimated amount for university fees associated with this program are available under the section Finance your studies. International students enrolled in a French-language program of study may be eligible for a differential tuition fee exemption.

Admission Requirements

To be eligible, candidates must:

• Have one of the following:
  • A bachelors degree with a specialization or a major (or equivalent) in science with a minimum average of 75% (B+).
  • An MD (Doctor of Medicine) degree with a minimum average of 75% (B+).
  • A DVM (Doctor of Veterinary Medicine) degree with a minimum average of 75% (B+).
• Demonstrate a good academic performance in previous studies as shown by official transcripts, research reports, abstracts or any other documents demonstrating research skills.
• Identify at least one professor who is willing to supervise your research and thesis.

Language Requirements

Applicants must be able to understand and fluently speak the language of instruction in the program to which they are applying. Proof of linguistic proficiency may be required.

Program Requirements

Students must meet the following requirements for the masters with collaborative specialization:

• Compulsory Courses (BCH):
  • MED 8166: Professionalism and Professional Skills
  • 3 optional course units from the list of approved biochemistry (BCH) courses at the 8000 or 9000 level
• Seminar:
  • BCH 5366: MSc Seminar 1
• Compulsory Courses (HMG):
  • 3 course units from:
    • HMG 8103: Advanced Topics in the Molecular Biology of Human Diseases I
    • HMG 8105: Advanced Topics in the Molecular Biology of Human Diseases II
    • HMG 8600: Special Topics in Human and Molecular Genetics
• Thesis:
  • THM 7999: Master's Thesis

Minimum Requirements

The passing grade in all courses is C+. Students who fail 6 units must withdraw from the program.

Fast-Track from Masters to PhD

Students enrolled in the masters program in Biochemistry at the University of Ottawa may be eligible to fast-track directly into the doctoral program without writing a masters thesis.

Research at the University of Ottawa

Located in the heart of Canadas capital, a few steps away from Parliament Hill, the University of Ottawa ranks among Canadas top 10 research universities. Our research is founded on excellence, relevance and impact and is conducted in a spirit of equity, diversity and inclusion.

Research at the Faculty of Medicine

The Faculty of Medicine has a long history of conducting both basic and clinical research of the highest quality. Many of our high profile research projects are conducted in partnership with affiliated-teaching hospitals and research institutes. These partnerships lead to biomedical discoveries that have a significant impact on health care.

Facilities, Research Centres and Institutes at the Faculty of Medicine

• Centre for Neural Dynamics
• University of Ottawa Centre for Neuromuscular Disease
• Centre for Research in Biopharmaceuticals and Biotechnology
• Canadian Partnership for Stroke Recovery
• Kidney Research Centre
• University of Ottawa Skills and Simulation Centre
• Medical Devices Innovation Institute
• Ottawa Institute of Systems Biology
• University of Ottawa Brain and Mind Research Institute

Courses

BCH 5101 Analysis of -Omics Data (3 units)

Theoretical and practical aspects of various methods currently used to analyze the plethora mountain of omics data.

BCH 5102 Principles of Biomanufacturing (3 units)

This course will cover the fundamental biological principles impacting the development and efficacy of biotherapeutics.

BCH 5103 Seminar in Biomanufacturing and Commercialization (3 units)

Seminars on topics of current interest in biomanufacturing and related subjects.

BCH 5366 MSc Seminar (3 units)

Attendance and participation in the annual BMI Student Symposium and BMI Poster Day, attendance at BMI seminars relevant to Biochemistry.

BCH 5501 Analyse des données omiques (3 crédits)

Les aspects théoriques et pratiques des méthodes actuellement utilisées pour l'analyse des données omiques.

BCH 8101 Physical and Chemical Methods in Biochemistry (3 units)

Current applications of physical and chemical methods to the study of macromolecule structure-function relationships.

BCH 8102 Selected Topics in Protein Structure and Function (3 units)

An advanced study of recent literature dealing with structure-function relationships in selected proteins.

BCH 8103 Advanced Topics in Gene Expression and Protein Synthesis (3 units)

An advanced study of the recent literature dealing with the chemistry, metabolism and function of nucleic acids, the biosynthesis of proteins, biochemical and genetic control mechanisms, genetic engineering and the control of gene expression.

BCH 8104 Advanced Topics in Cell Regulation (3 units)

An advanced study of recent literature dealing with signal transduction processes and the regulation of metabolism, cell proliferation and differentiation.

BCH 8105 Advanced Topics in Molecular Biology of Human Diseases (3 units)

Topics will be selected and representative of current developments in the field.

BCH 8106 Mitochondrial Medicine: Theory and Approaches (3 units)

An advanced study of the recent literature dealing with metabolism, nutrition and metabolic control theory, with emphasis on both whole body and cell metabolism in metabolic and nutritional disorders.

BCH 8107 Advanced Topics in Lipid Metabolism and Disease (3 units)

An advanced study of the recent literature dealing with the role of lipids in both normal physiology and pathophysiology.

BCH 8108 Advanced Methods of Macro-Molecular Structure Determination (3 units)

A detailed examination of modern methods used to determine the structures of proteins, nucleic acids, and carbohydrates.

BCH 8109 Advanced Topics in Cell Death (3 units)

Molecular mechanisms of cell death.

BCH 8110 Advanced Topics in Systems Biology (3 units)

Recent advances in genomics, proteomics, bioinformatics, and neuroinformatics.

BCH 8111 Chromosome and Chromatin Biology (3 units)

Higher order chromosome structure and chromatin remodeling and their impact on regulation of gene expression.

BCH 8114 Advanced Topics in the Cell Cycle (3 units)

Mechanisms of cell cycle regulation.

BCH 8116 Model Organisms and Systems Biology (3 units)

Utilization of model organisms in the development and advancement of the systems biology field.

BCH 8117 Advanced Topics Relating to the Cell Cytoskeleton and Membranes (3 units)

Advanced study of recent literature dealing with the mammalian cellular cytoskeleton and membrane.

BCH 8120 Advanced Topics in Immunometabolism (3 units)

An advanced study of the recent literature dealing with the field of immunometabolism.

BCH 8134 Structure and Expression of Eukaryotic and Prokaryotic Genomes (3 units)

Sequencing of eukaryote and prokaryote genomes with emphasis on recent technologies.

BCH 8165 Special Topics in Biochemistry (3 units)

A survey of recent advances in selected areas of biochemistry.

BCH 8166 Special Topics in Biochemistry II (3 units)

A survey of recent advances in selected areas of biochemistry.

BCH 8213S Seminars (2 crédits / 2 units)

Compulsory for second-year graduate students.

BCH 8214S Seminars (2 crédits / 2 units)

Compulsory for third-year graduate students.

BCH 8310 Current Topics in RNA Molecular Biology (3 units)

Properties, mechanisms associated with regulation and the functions of RNAs and Ribonucleoprotein (RNPs).

BCH 8366 PhD Seminar (3 units)

Attendance and participation in the annual BMI Student Symposium and BMI Poster Day.

BCH 8511 Biologie des chromosomes et de la chromatine (3 crédits)

Organisation de la structure des chromosomes et le remodelage de la chromatine.

BCH 8534 Structure et expression des génomes procaryotes et eucaryotes (3 crédits)

Le séquençage des génomes eucaryotes et procaryotes avec un accent particulier sur les technologies récentes.

BCH 9998 Examen de synthčse (doctorat) / Comprehensive-Examination (PhD)

Ŕ l'intention des étudiants inscrits au programme de Ph.D.

HMG 8103 Advanced Topics in the Molecular Biology of Human Diseases I (3 units)

Topics will be selected and representative of current developments in the field.

HMG 8105 Advanced Topics in the Molecular Biology of Human Diseases II (3 units)

Topics will be selected and representative of current developments in the field.

HMG 8106 Clinical Cytogenomics (3 units)

Comprehensive review of the basic principles and technologies in cytogenomics.

HMG 8107 Clinical Biochemical Genetics (3 units)

Presentation of the biomechanical and molecular bases of inborn errors of metabolism.

HMG 8108 Clinical Molecular Genetics (3 units)

Comprehensive review of all aspects of clinical molecular genetics.

HMG 8506 Cytogénomique clinique (3 crédits)

Revue exhaustive des principes de base et des techniques en cytogénomique.

HMG 8507 Génétique biochimique clinique (3 crédits)

Présentation des bases biochimiques et moléculaires des maladies innées du métabolisme.

HMG 8508 Génétique moléculaire clinique (3 crédits)

Revue exhaustive de tous les aspects de la génétique moléculaire clinique.

HMG 8600 Special Topics in Human and Molecular Genetics (3 crédits)

Current topics in molecular genetics, developmental genetics, cancer genetics, neurogenetics, population genetics, clinical genetics and other areas depending on available expertise and interest expressed.