Omics Techniques and Technologies and their Application to Genomic Medicine

Program Overview

Participants develop proficiency in interpreting and applying these techniques to genomic medicine applications such as cancer research and common inherited diseases, gaining practical understanding for clinical laboratory practice. The course features interactive teachings by esteemed faculty and hands-on lab sessions.

Program Outline

Degree Overview:

The "Omics Techniques and Technologies and their Application to Genomic Medicine" is a five-day postgraduate microcredential designed for individuals seeking a comprehensive understanding of 'omics' techniques and technologies. The program aims to explore the interpretation and application of these techniques in key areas of genomic medicine, including cancer, common and rare inherited diseases, infectious diseases, and research.

Objectives:

• Develop a strong foundation in 'omics' techniques and technologies.
• Understand the interpretation and application of 'omics' in genomic medicine.
• Gain an introduction to metabolomics and proteomics, their role in interpreting genomic data, and their application in discovering disease biomarkers.

Outline:

Content:

• Basis of genotyping and detection of genetic variation.

• Whole exome and whole genome sequencing: This includes library preparation methods, sequencing chemistries, and platforms.
• Single nucleotide variations (SNVs)
• Small insertions and deletions (indels)
• Copy number variants (CNVs)
• Rearrangements (including Sanger sequencing, qFPCR, MLPA, aCGH, FISH)
• Genomic testing strategies: This covers gene-focused, multiple genes, whole genome or exome, and detection of sequence, copy number, or rearrangements.

• Application of functional studies to the interpretation of pathogenicity.

Structure:

• The microcredential is delivered over five days.

Faculty:

• Dr Samantha Butler: Principal Clinical Scientist, Familial Cancer and Molecular Pathology, West Midlands

Other:

• Prerequisites:
• A good honors degree in a life sciences subject is recommended.
• Applicants with alternative qualifications and professional experience within the health service or other relevant backgrounds will be considered.
• Students should either take the "Fundamentals in Human Genetics and Genomics" module first or demonstrate equivalent knowledge and understanding.
• Credits: 15 masters level credits
• Attendance: Required
• Mode: Face-to-face
• Cost:
• Home: £1000
• International: £1830
• Start Date: 5-6 October, and 11-13 October 2023