Program Overview

Advanced Bioprocess Control, Data and PAT

Overview

This five-day course provides in-depth training in the benefits, strategies, and concepts of control in industrial biomanufacturing, including the challenges and operational complexity in maintaining productivity, efficiency, and quality in the bioprocessing environment and on multi-unit production lines.

Course Details

What You Study

• Module 1 - Perfecting Conventional Control
  • Introduction to biotechnology and bioprocessing
  • The systems engineering landscape in bioprocessing
  • Instrumentation including PAT
  • Control concepts, performance metrics and PID control
  • Strategy design in advanced conventional control
• Module 2 - Performance Assessment and Quality Improvement
  • Control system cost benefit analysis
  • Introduction to design of experiments
  • Statistical process control methods
  • Lean Six Sigma
  • Control and automation in the validated environment
• Module 3 - Maximising Information from Available Data
  • Data pipelining
  • Systems modelling concepts
  • Data modelling in bioprocessing
  • Visualisation of process development bioprocess data from small bioreactors by multivariate data analysis with SIMCA
  • Monitoring of production bioprocess data by multivariate data analysis with SIMCA-online
• Module 4 - Advanced Approaches: Process Analytical Technologies and Control Opportunities, Benefits, and Implementation
  • Process analytical technologies: Process spectroscopy and its role in control improvement
  • Process analytical technologies: Online measurement of biomass and case study examples
  • Process analytical technologies: Rapid measurements of quality of product
  • Automation case study
• Module 5 - Bioprocess Simulation and Automation in Development
  • Bioprocess simulation
  • Bioreactor automation
  • Mechanistic modelling of chromatography
  • The future of bioprocess automation

How You Learn

This four-day course is delivered through a combination of lectures, workshops, and practical sessions. The content covers theoretical aspects and practical techniques in biomanufacturing, including process control, automation, and process analytical technology (PAT).

How You Are Assessed

No assessment required.

Entry Requirements

• At least 3 years’ experience within the biomanufacturing industry.

Employability

• Completing this course can benefit careers in biomanufacturing, process development, and R&D. It is particularly useful for roles focused on process control, automation, and data analysis in the bioprocessing industry.

Part-time Entry

• Fee for applicants: £2,950 plus VAT
• Length: 5 days
• Start date: TBC