Program Overview

Program Overview

The William Harvey Research Institute at Queen Mary University of London offers various programs in the field of endocrinology and diabetes.

MSc in Clinical Endocrinology and Diabetes

The MSc in Clinical Endocrinology and Diabetes is an award-winning program that has educated over 300 students from six continents. The program is available in both distance-learning and campus-based formats.

Program Details

• The distance-learning MSc in Endocrinology and Diabetes is designed for students who cannot attend campus-based programs.
• The campus-based MSc in Clinical Endocrinology incorporates an intercalated MSc in Clinical Endocrinology for students undertaking MBBS.
• The program has received national recognition and has been awarded for its contribution to the field of endocrinology.
• Student feedback indicates that the program is career-enhancing.

Research Areas

• Cardiovascular
• Endocrinology
• Inflammation
• Featured research
• Core Facilities
• Fundraising

Research Centres

• Centre for Advanced Cardiovascular Imaging
• Centre for Biochemical Pharmacology
• Centre for Cardiovascular Medicine and Devices
• Centre for Clinical Pharmacology and Precision Medicine
• Centre for Endocrinology
• Centre for Experimental Medicine & Rheumatology
• Centre for Microvascular Research
• Centre for Translational Medicine and Therapeutics

Study Options

• Undergraduate
• Postgraduate Taught
• Postgraduate Research

People

• Academic staff
• Postdoctoral Researchers
• Support staff

News and Events

• News
• Events
• WHRI Magazine

Clinical Activities

• William Harvey Clinical Research Centre (CRC)
• William Harvey Heart Centre
• Barts Cardiovascular Clinical Trials Unit (CVCTU)

Patient and Public Engagement

• Barts and Queen Mary Science Festival
• Let's Talk Hearts
• Pint of Science
• WHRI Work Experience Programme
• AutoImmunity Research Advisors Group (AIRA)
• Patient & Public Engagement activities

Key Publications

• Demonstration of how BRAF and, more generally MAPK signalling, contribute to pituitary development.
• Discovery of co-driver pathogenic somatic mutations in aldosterone-producing adenomas of women presenting with hypertension in the first trimester of pregnancy.
• Discovery of a novel genetic cause of delayed puberty in boys.
• Discovery that the neurohormone dopamine signals through a specific receptor-combination(s) in early-stage Huntington’s disease.
• Demonstrated that metformin reduces the adverse metabolic side-effects of glucocorticoids.
• Proof-of-principle that pro-active, clinical surveillance of asymptomatic people with mutations has real clinical benefit.
• Recognition that one of the most common mouse sub-strain used in the research community has a mutation causing dilated cardiomyopathy.
• Discovery that contrary to expectations that the pseudokinase Tribbles 1 in arterial macrophages promotes uptake of atherogenic lipoproteins.
• Reader’s choice award 2019 for the most significant contribution to the field in 2018.
• Key mechanistic discoveries.
• Development of novel method for making steroidogenic cells from fibroblasts, blood- and urine-derived cells.
• Development of a conceptual model for studying feedback loops regulating the architecture of dermis.
• Discovery MRAP2 in the hypothalamic paraventricular nucleus that regulates food intake and energy expenditure.
• Identification of a heterozygous germline mutation in a β-cell–enriched transcription factor.
• Discovery that pseudohypoxia associated with genetic causes of pheochromocytoma and paragangliomas disrupts primary cilia-mediated signalling pathways.
• Discovery of key molecular mechanism underlying the neurodegenerative disease ARSACS.
• Discovery that the hypothalamic-derived hormone kisspeptin binds to specific receptors in the fetal adrenal gland.
• First description of a novel syndrome of adrenal insufficiency and steroid-resistant nephrotic syndrome.
• Identification of a genetic cause of delayed puberty highlights the contribution of a previously uncharacterised protein.
• Established that the repressor functions of Transcription factor 7-like 1 are required for the development of the hypothalmus-pituary axis.
• Discovered novel role for a collagen XVIII isoform in adipose tissue accrual and metabolism.