Program Overview

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Cancer and Blood Disorders Institute

The Cancer and Blood Disorders Institute at Johns Hopkins All Children's Hospital offers a comprehensive range of programs and services for the diagnosis, treatment, and management of cancer and blood disorders in children.

Programs and Services

• Adolescent & Young Adult Oncology Program
• Benign Hematology
• Blood Cancers
• CanSurvive Clinic
• Car T-Cell Therapy
• Center for Cell and Gene Therapy for Non-Malignant Conditions
• Cancer and Blood Disorders Hospitalists
• Pediatric Neuro-Oncology
• Solid Tumor Program
• Stem Cell and Bone Marrow Transplant

Benign Hematology

The Benign Hematology program includes:

• Hemophilia and Bleeding Disorders Treatment Center
• Pediatric Thrombosis Program
• Sickle Cell Disease Program

Blood Cancers

The Blood Cancers program offers:

• Overview of blood cancers
• Blood Cancer Clinical Trials
• Childhood Leukemia
• Childhood Lymphoma
• Meet the Blood Cancers Team

CanSurvive Clinic

The CanSurvive Clinic provides:

• Additional Resources
• Meet Our CanSurvive Clinic Team
• Passport for Care
• Survivorship Facts and Guidelines

Car T-Cell Therapy

The Car T-Cell Therapy program includes:

• Overview
• Active Clinical Trials and Research Studies
• Meet the CAR-T Cell Team

Center for Cell and Gene Therapy for Non-Malignant Conditions

The Center for Cell and Gene Therapy offers:

• Overview
• Active Clinical Trials and Research Studies
• Meet the Cell and Gene Therapy Team

Pediatric Neuro-Oncology

The Pediatric Neuro-Oncology program provides:

• Overview
• Meet the Neuro-Oncology Team
• Neurofibromatosis Education Symposium
• Research

Solid Tumor Program

The Solid Tumor Program includes:

• Overview
• Meet Our Solid Tumor Team
• Solid Tumor Clinical Trials

Stem Cell and Bone Marrow Transplant

The Stem Cell and Bone Marrow Transplant program offers:

• Overview
• Stem Cell and Bone Marrow Transplant: Clinical Trials
• Stem Cell and Bone Marrow Transplant: Conditions We Treat
• Blood and Marrow Transplant Team

Childhood Leukemia

Childhood leukemia is a blood cancer that causes abnormal white blood cells to grow in the bone marrow and move into the bloodstream.

What Is Leukemia?

Leukemia is a type of cancer that affects the blood and bone marrow. It is characterized by the uncontrolled growth of abnormal white blood cells, which can lead to a range of symptoms and health problems.

What Causes Leukemia in Children?

The exact cause of leukemia in children is not known, but it is thought to be related to genetic mutations and other factors.

What Are Symptoms of Leukemia in Children?

Symptoms of leukemia in children can include:

• Loss of appetite or weight loss
• Bleeding easily
• Bone or joint pain
• Bruising easily
• Fatigue
• Fever
• Frequent infections
• Pale skin
• Shortness of breath
• Swollen lymph nodes

How Do We Diagnose Leukemia?

Diagnosis of leukemia typically involves a combination of physical examination, medical history, and laboratory tests, including:

• Complete blood count (CBC)
• Bone marrow aspiration and biopsy
• Lumbar puncture

Types of Childhood Leukemia

There are several types of childhood leukemia, including:

• Acute lymphoblastic leukemia (ALL)
• Acute myeloid leukemia (AML)
• Chronic myeloid leukemia (CML)

Leukemia Treatments We Offer

Treatment for leukemia depends on the type and stage of the disease, as well as the individual child's needs and overall health. Options may include chemotherapy, radiation therapy, bone marrow transplant, and other therapies.