Program Overview

APPLIED MEDICAL TECHNICAL SCIENCES (BIOMEDICAL LABORATORY)

Program Overview

The Applied Medical Technical Sciences (Biomedical Laboratory) program is designed to provide students with a deep understanding of the area of biomedical laboratory sciences and techniques. The program aims to equip students with the knowledge and skills necessary to work in diagnostic and translational research laboratories.

Learning Outcomes

The program aims to achieve the following learning outcomes:

• Deepening of knowledge relating to the area of the three-year degree course in Biomedical Laboratory Sciences and Techniques
• Understanding of organizational models for diagnostic and translational research laboratories
• Ability to apply tools for organizational analysis, monitoring, non-conformity management, and continuous improvement
• Understanding of the phases, regulations, and ethical principles of clinical trials and pharmaceutical development
• Ability to classify epidemiological studies and analyze ethical aspects of clinical trials
• Knowledge of advanced cytometry technologies for clinical analysis
• Study of omics in the medical field
• Introduction to Translational Medicine
• In-depth study of immunological diseases

Teaching Methods

The program will be delivered through lectures, which will be presented in person. The course content will be presented through slides, which will be uploaded to the university's online platform after each class. The assessment will include both written and oral exams.

Syllabus/Content

The program will cover the following topics:

• Clinical Trials: Planning and Regulations
  • Phases of clinical research trials
  • Fundamental principles: autonomy, beneficence, justice, and bioethics
  • Patients' Bill of Rights; Ethics Committee; Informed consent
  • Requirements for proper clinical trials: relevant regulations; drug development process and its phases
• Omics, Translational Medicine, and Immunological Diseases
  • Clinical applications of omics sciences (genomics, proteomics, etc.)
  • Introduction to Translational Medicine
  • Study of immune-mediated diseases: connective tissue disorders, ANA, lupus
• Laboratory Medicine as a Clinical Science
  • Understanding the role of Laboratory Medicine as a clinical discipline providing essential information in the diagnostic and therapeutic process
  • Overview of the types and functions of different clinical laboratories
• Immunometric Techniques and Biomarkers
  • Knowledge of main immunometric techniques for detecting antigens or antibodies: from non-tracer to tracer-based methods
  • Comparison between competitive and non-competitive assays
  • Analytical issues in immunoassays
  • Definition and clinical use of biomarkers
• Immune Response and Laboratory Evaluation
  • Understanding of humoral and cell-mediated immune responses
  • Role of the clinical laboratory in evaluating immunopathological processes
• Tumor Immunology and Immunotherapy
  • Key concepts in tumor immunology
  • Role of oncological immunotherapy as a new frontier in cancer treatment
• Plasma Proteins and Clinical Significance
  • Types and roles of plasma proteins as indicators of organ function
  • Understanding how protein alterations reveal diseases and help monitor their progression

Teachers and Exam Board

The program will be taught by the following instructors:

• Gilberto Filaci
• Daniela Fenoglio
• Maddalena Mastrogiacomo The exam board will be composed of the following members:
• Daniela Fenoglio (President)
• Luca Guastini (President)
• Lucio Marinelli (President)
• Luca Roccagliata (President)
• Federico Zaottini (President)
• Matteo Bauckneht
• Liliana Belgiolia
• Gilberto Filaci
• Filippo Marchi
• Mattia Riondato
• Alberto Stefano Tagliafico
• Maddalena Mastrogiacomo (President and Coordinator of Integrated Course)

Lessons

The program will start in the second semester of the first year. The class schedule will be available on the university's online platform.

Exams

The exam will include both oral and written components. The university will follow the regulations established for the evaluation of students with Specific Learning Disorders (SLD) or other special educational needs.